Piperazine-1,4-dicarbonyl dichloride - Names and Identifiers
Piperazine-1,4-dicarbonyl dichloride - Physico-chemical Properties
Piperazine-1,4-dicarbonyl dichloride - Upstream Downstream Industry
Piperazine-1,4-dicarbonyl dichloride - Introduction
1,4-piperazinedicarbonyl CHLORIDE(1,4-dipyrrolyldicarbonyl CHLORIDE) is an organic compound with the chemical formula C8H10Cl2N2O2. It is a colorless to light yellow crystal, soluble in organic solvents such as chloroform and dichloromethane.
1,4-piperazinedicarbonyl CHLORIDE is mainly used for the synthesis of carboxylic acid derivatives in organic synthesis reactions. It can be used as a reagent for the synthesis of acylated products, acylated products and hydrazides. Because of its ability to form acylated intermediates, it has important applications in the field of pharmaceutical synthesis and organic synthesis.
The preparation method of 1,4-piperazinedicarbonyl CHLORIDE is usually completed by reacting 1,4-dicarbonylcyclohexane and thionyl CHLORIDE as an intermediate. First, 1,4-dicarbonylcyclohexane is reacted with thionyl chloride under basic conditions to give 1,4-dicarbonylcyclohexanoyl chloride. A base is then added to the reactant to neutralize the acidity to give the target product, 1,4-piperazinedicarbonyl CHLORIDE.
Regarding safety information, 1,4-piperazinedicarbonyl CHLORIDE is a commonly used reagent in organic synthesis, so the following points should be paid attention to during handling and storage: direct contact with the skin should be avoided, avoid inhaling its vapors or dust, and wear protective gloves, glasses and work clothes if necessary. If contact or inhalation occurs, rinse immediately with plenty of water and consult a doctor.
Last Update:2024-04-09 21:01:54